This lists songs that hit number one on the charts in the US during 1968. If a song spent nonconsecutive weeks at number one, the number of weeks for each occurrence at the top is shown in parenthesis.
| Date | Artist - Title | Weeks at #1 |
| December 24 1967 – January 13 1968 | Beatles - Hello, Goodbye | 3 |
| January 14 – 27 1968 | John Fred and His Playboy Band - Judy in Disguise (With Glasses) | 2 |
| January 28 – February 3 1968 | Lemon Pipers - Green Tambourine | 1 |
| February 4 – March 9 1968 | Paul Mauriat - Love Is Blue | 5 |
| March 10 – April 6 1968 | Otis Redding - Sitting On The Dock Of The Bay | 4 |
| April 7 – May 11 1968 | Bobby Goldsboro - Honey | 5 |
| May 12 – 25 1968 | Archie Bell and The Drells - Tighten Up | 2 |
| May 26 – June 15 1968 | Simon and Garfunkel - Mrs. Robinson | 3 |
| June 16 – July 13 1968 | Herb Alpert - This Guy's In Love With You | 4 |
| July 14 – 27 1968 | Hugh Masekela - Grazing In The Grass | 2 |
| July 28 – August 10 1968 | Doors - Hello, I Love You | 2 |
| August 11 – September 14 1968 | Rascals - People Got To Be Free | 5 |
| September 15 – 21 1968 | Jeannie C. Riley - Harper Valley P.T.A. | 1 |
| September 22 – November 23 1968 | Beatles - Hey Jude | 9 |
| November 24 – December 7 1968 | Supremes - Love Child | 2 |
| December 8 1968 – January 25 1969 | Marvin Gaye - I Heard It Through The Grapevine | 7 |
16 different songs hit number one in the US during 1968.
Top 5 Songs of 1968

1: Beatles - Hey Jude
2: Paul Mauriat - Love Is Blue (L'Amour Est Bleu)
3: Bobby Goldsboro - Honey
4: Otis Redding - (Sittin' On) The Dock Of The Bay
5: Rascals - People Got To Be Free
2: Paul Mauriat - Love Is Blue (L'Amour Est Bleu)
3: Bobby Goldsboro - Honey
4: Otis Redding - (Sittin' On) The Dock Of The Bay
5: Rascals - People Got To Be Free